Activists
- Candy Lightner - founder of Mothers Against Drunk Driving and former president of the American-Arab Anti-Discrimination Committee
- James Zogby - founder of Arab-American Institute
- John Zogby - American political pollster
- Ralph Nader - consumer rights activist abd US presidential candidate
- Rose Nader - school teacher and activist
Artists
- Elie Saab - fashion designer.
- Joseph Philippe Karam - architect
- Paul Zgheib - photographer
- Reem Acra - fashion designer
- Sam Maloof - woodworker
Entrepreneurs
- Carlos Slim Helu
- Edmond Safra - founder of Republic Bank of New York and Banco Safra in Brazil, born in Aley, Lebanon
- Jacques Nasser - ex-CEO of Ford Motors, born in Lebanon
- Mario Kassar - co-founder of Carolco Pictures
- Nicolas Hayek - the 'father of Swatch' and CEO of Smart
- Paul Orfalea - founder of Kinko's
- Sam Hammam - owner of Cardiff City F.C.
Film, Theatre, Television and Radio Personalities
- Amy Yasbeck - Lebanese-American film and television actress, widow of actor John Ritter
- Arsinée Khanjian - actress (Lebanese-born, Armenian ethnicity)
- Casey Kasem - television personality of Druze Lebanese descent
- Danny Thomas - nightclub comedian and television actor
- Dom Joly - comedian, presenter and journalist
- Georgina Rizk - Miss Universe 1971
- James Stacy - actor (Laramie)
- Jamie Farr - actor of M*A*S*H fame
- Joseph Barbera and William Hanna - Hanna-Barbera
- Kathy Najimy - actress
- Keanu Reeves - actor
- Khrystyne Haje - actress
- Lili Estefan - Cuban American television hostess
- Mario Kassar - film producer
- Salma Hayek - actress (Lebanese father and Mexican mother)
- Tom Shadyac - director
- Tony Shalhoub - television and film actor
- Wentworth Miller- television actor
Military
- George Joulwan - US general, SACEUR
- Hisham Jaber - former Commander of Beirut
- John Abizaid - US general, CENTCOM Commander
Musicians
- Amal Hijazi - pop-singer and dancer
- Assi Rahbani - composer
- Elissa - pop singer
- Emilio Estefan - Lebanese parents
- Fairouz, born Nouhad Haddad - singer
- Frank Zappa
- Gabriel Yared, international composer
- Guy Béart - singer
- Haifa Wehbe - singer
- Herbert Khaury - (Tiny Tim), singer, ukulele player (Lebanese father)
- John Dolmayan - System of a Down drummer (Lebanese-born, Armenian ethnicity)
- Karl Wolf - born in Lebanon
- K-Maro - Canadian rapper of Lebanese origin
- Mansour Rahbani - composer
- Marcel Khalife - singer, orchestral composer, oud player
- Massari - Lebanese pop and hip-hop singer who grew up in Canada.
- Matthieu Chedid - Lebanese-French rock/blues songwriter and singer
- Mika - (Mica Penniman), singer
- Myriam Fares - singer
- Najwa Karam - singer
- Nancy Ajram - singer
- Nawal Al Zoghbi - singer
- Pascale Machaalani - singer
- Paul Anka - singer
- Sabah - born Janet Feghali from Wadi Al Shahrour, singer and actress
- Sammy Hagar - former lead vocalist for the rock band Van Halen
- Sarbel - Greek singer, born in London to a Lebanese mother
- Serj Tankian - System of a Down vocalist,guitarist ,political activist (Lebanese-born, Armenian ethnicity)
- Setrak Setrakian - composer and pianist (Armenian ethnicity)
- Shakira - Colombian singer/songwriter (Lebanese father from Zahle, Colombian mother of Catalan descent)
- Soraya - American-Colombian-Lebanese singer/songwriter (Lebanese mother)
- Tony Hajjar - drummer
- Wadih Safi - musician and singer
- Yfrah Neaman - violinist
- Ziad Rahbani - composer
Scientists
- Elias J. Corey - Chemist, Nobel Prize in Chemistry (1990)
- Michael Ellis DeBakey - pioneering cardiovascular surgeon and researcher
- Peter Medawar - Nobel Prize Physiology /Medicine 1960 for immune system (British father, Lebanese mother)
- Sir Michael Atiyah - (Lebanese British father) - mathematician, Fields Medal (1966), Abel Prize (2004)
Sports
- Bill George - NFL Hall of Famer
- Bobby Rahal - Winner of the Indianapolis 500
- Brian Habib - former NFL player
- Darren Flutie - former CFL player
- Doug Flutie - former NFL and CFL player
- Ed Hatoum - former NHL player
- Eddie Elias - founder of the Bowling Association of America
- Fadi El Khatib - Lebanese basketball Player
- Faryd Aly Mondragón - Colombian goalkeeper with Lebanese descent
- Frank Skaff - former manager of the Detroit Tigers (MLB)
- Fred Saigh - former owner of the St. Louis Cardinals (MLB)
- Fuad Reveiz - former NFL player
- George Farah - 19th Mr Olympia 2002
- George Mourad - Famous soccer player in Sweden (IFK Göteborg)
- Hazem El Masri - NRL player
- Jeff George - former NFL player
- Joe Lahoud - former Major League Baseball player
- Joe Robbie - former owner of the Miami Dolphins (NFL)
- John Jaha - former MLB player
- Rich Kotite - former NFL coach
- Rony Seikaly, Lebanese American, former NBA basketball player
- Rudy Haddad - french footballer
- Sammy Farha - Professional Poker Player, 2-time WSOP bracelet winner
- Steve Kerr - former NBA star (Lebanese-born)
Writers and Journalists
- Ahmad Reda - linguist
- Amin Maalouf - writer, Prix Goncourt (1993)
- Andree Chedid - poet
- Ann-Marie MacDonald - writer (Lebanese mother)
- David Malouf - Australian author (Lebanese father, English-Sephardic Jewish mother of Portuguese descent)
- Edward Atiyah - writer
- Elias Khoury - novelist
- Gebran Tueni - former editor and publisher of An-Nahar newspaper
- Ghassan Tueni - editor in chief of An-Nahar newspaper, legislator
- Gibran Khalil Gibran - poet and writer, "The Prophet"
- May Chidiac - journalist
- Muhammad Jaber - writer and historian
- Neal Conan - radio journalist (Lebanese-born)
- Philip Khuri Hitti
- Rabih Alameddine - painter, novelist
- Samir Kassir - journalist of An-Nahar newspaper and writer
- Wadih Saadeh - journalist, poet and writer
- William Peter Blatty - writer, "The Exorcist"